Proteomic Mining in Dysplastic Liver of WHV/c-myc Mice:Insights and Indicators for Early Hepatocarcinogenesis
作者单位：Key Laboratory of Systems BiologyInstitute of Biochemistry and Cell BiologyShanghai Institutes for Biological SciencesChinese Academy of Sciences
会议名称：《21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology》
会议日期：2009年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要：正Clinically,early detection of cancers such as HCC is highly desirable,but very challenging,due to the asymptomatic process of ***-prone transgenic mice of invariable oncogenesis can offer stable and powerful reference for analyzing cancer initiation,thus also hold greater promise for discovering putative early HCC *** a label-free proteomic quantitation strategy by spectral counts,we comprehensively investigated the protein expression profile in three two-month-old WHV/