Secalonic acid D reduced the percentage of side populations by down-regulating the expression of ABCG2
作者单位:State Key Laboratory of Oncology in Southern ChinaCancer CenterSun Yat-senUniversity
会议名称:《2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议》
会议日期:2013年
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要:Background:The side population cells characterized by the ability to transport Hoechst 33342 out of cells have been identified as cancer stem-like ***2 is found to confer the side population(SP) phenotype,multidrug resistance(MDR) and tumor *** as to test the potent effect of secalonic acid D(SAD) on MDR and SP cells,we carried out this ***:The cytotoxicity of SAD was determined by *** expression level