Protocol design for the EXPLORER study of the efficacy and safety of rituximab in patients with moderate to severe SLE
作者单位：Oklahoma Medical Research FoundationOklahoma CityOklahoma GenentechInc.South San FranciscoCAUSA
会议名称：《The 8th International Congress on SLE》
会议日期：2007年
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
摘 要：正Purpose:B cells play multiple roles in SLE,including both autoantibody generation and autoantibody-independent ***,a monoclonal antibody that binds to CD20 and induces peripheral B cell depletion,is currently approved for the treatment of some categories of patients with CD20+B cell lymphoma or rheumatoid ***