Pleiotrophin fights Brd2 for neuronal differentiation

作     者：Pablo Garcia-Gutierrez Mario Garcia-Dominguez 

作者机构：Stem Cells DepartmentAndalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) (Consejo Superior de Investigaciones Cientificas (CSIC)Junta de AndalucíaUniversidad de SevillaUniversidad Pablo de Olavide).Av.Americo Vespucio s/n41092 SevilleSpain 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2015年第10卷第4期

页      面：544-546页

核心收录：

学科分类：0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 071006[理学-神经生物学] 

基　　金：supported by Ministry of Economy and Competitiveness,Spain(MINECO),grant number BFU2012-37304 by Junta de Andalucía,Spain,grant number P12-CTS-2064 

主　　题：Pleiotrophin fights Brd2 for neuronal differentiation cycle 

摘      要：Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive C-terminal extra terminal domain （ET） （Belkina and Denis, 2012; Shi and Vakoc, 2014）. Bromodomains are involved in recognizing acetylated histone tails and other acetylated proteins while the ET domain has been implicated in protein-protein interaction.