Early operation for fulminant acute pancreatitis： a possible way to decrease mortality

作     者：YANG Dong-jie HE Yu-long CAI Shi-rong PENG Jian-jun ZHANG Chang-hua ZHAN Wen-hua 

作者机构：Department of Gastrointestinal-pancreatic Surgery First Affiliated Hospital of Sun Yat-Sen University Guangzhou Guangdong 510080 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2009年第122卷第13期

页      面：1492-1494页

核心收录：

学科分类：090603[农学-临床兽医学] 09[农学] 0906[农学-兽医学] 

主　　题：fulminant acute pancreatitis early operation mortality 

摘      要：Background Although the indication controversial, our experience of surgical patients. and the timing for surgery in fulminant treatment for fulminant acute pancreatitis acute pancreatitis （FAP） are still may help improve the outcome for Methods The clinical data of twenty-six patients with FAP from January 1, 2001 to October 1, 2005 were analyzed. The diagnostic criteria fitted the 2007 Guidelines for the Management of Severe Acute Pancreatitis by the Chinese Medical Association. Results Twenty-six patients with FAP received surgical debridement, with a mortality rate of 42.3% （11/26）. The postoperative mortalities in the 〉72 hour operation group and the 〈72 hour operation group were highly significantly different （7/8 vs 22.2% （4/18）, respectively）. Conclusions Early surgery may reduce the intraabdominal pressure and prevent the deterioration of FAP. An operation within 72 hours from the onset of symptoms might decrease the mortality of the disease.