Recent advances of morphology adaptive nanomaterials for anti-cancer drug delivery

作     者：Dongbing Cheng Zengying Qiao Lixue Xuan Hao Wang Dongbing Cheng;Zengying Qiao;Lixue Xuan;Hao Wang

作者机构：School of Chemistry Chemical Engineering & Life Science Wuhan University of Technology CAS Center for Excellence in Nanoscience Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology (NCNST) Department of Breast Surgery Nation Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Henan Institute of Advanced Technology Zhengzhou University 

出 版 物：《Progress in Natural Science:Materials International》 (自然科学进展·国际材料(英文))

年 卷 期：2020年第30卷第5期

页      面：555-566页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 10[医学] 0702[理学-物理学] 

基　　金：supported by National Natural Science Foundation of China (21704020  21674027  31870998  51573032  81672630 and 51725302) 

主　　题：red Recent advances of morphology adaptive nanomaterials for anti-cancer drug delivery 

摘      要：The morphology of nanomaterials combines the characteristics of their size, shape and spatial structure. Owing to the improved spatiotemporal control of the nanocarriers for anti-cancer drug delivery, the morphology adaptive nanomaterials have received tremendous attention in the field of nanomedicine, while they are able to respond through chemical or physical change. In this review, we summarize the recent advancements of morphology adaptive nanomaterials and their application in anti-cancer drug delivery system, wherein the size, shape and spatial structure of nanocarriers can be changed to adapt the complex living system, thus overcoming the pathological barriers in drug delivery. The overview of the recent examples shows that each step of delivery process can be improved by the morphology adaption, which represents the great potential for clinic translation of morphology adaptive nanomaterials.