Hepatocellular carcinoma clinical update: Current standards and therapeutic strategies

作     者：Steven D.Colquhoun Steven D.Colquhoun

作者机构：Department of SurgeryUniversity of California DavisSacramentoCAUSA 

出 版 物：《Liver Research》 (肝脏研究（英文）)

年 卷 期：2020年第4卷第4期

页      面：180-190页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Hepatocellular carcinoma(HCC) Ablation Transarterial chemoembolization(TACE) High intensity focused ultrasound(HIFU) Stereotactic body radiation therapy(SBRT) Irreversible electroporation(IRE) Liver surgery Liver transplantation 

摘      要：Hepatocellular carcinoma(HCC)accounts for the vast majority of primary hepatic *** overall incidence of this disease has always been significant,but in recent years it has continued to rise,now making HCC one of the leading causes of cancer deaths ***,research into the mechanisms of carcinogenesis and treatment options for this disease has also been progressing *** the future for new insights and therapies appears more promising than ever,it also remains important to understand both the nature of HCC and the current state-of-the-art for treating affected *** surgery is often considered to be a first choice,many patients present with extensive disease and are therefore not operative ***,significant clinical advances over the last decade have contributed a number of new or improved treatment *** of these treatments require expertise from a variety of different clinical ***,managing patients with HCC has rapidly become a multi-modality,multi-disciplinary endeavor in which the details of each in-dividual’s circumstance can greatly impact outcomes,and strategies can be quite *** purpose of this review is to provide a perspective on the disease itself,the patients who become afflicted,the spectrum of currently available treatment options,and the strategies for their optimal *** knowledge can be critically important as new data become available on the research front.