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Is There Any Relationship between Maternal Vitamin D Levels and Asymptomatic Bacteriuria? A Preliminary Study

Is There Any Relationship between Maternal Vitamin D Levels and Asymptomatic Bacteriuria? A Preliminary Study

作     者:Emel Kurtoglu Ozdes Bahattin Avci Samettin Celik Gokhan Ocal Serap Polat Feyza Munevver Yaran Taskin Ozdes Migraci Tosun Arif Kokcu Emel Kurtoglu Ozdes;Bahattin Avci;Samettin Celik;Gokhan Ocal;Serap Polat;Feyza Munevver Yaran;Taskin Ozdes;Migraci Tosun;Arif Kokcu

作者机构:Department of Obstetrics and Gynecology Memorial Hizmet Hospital Istanbul Turkey Department of Biochemistry Faculty of Medicine Ondokuz Mayis University Samsun Turkey Maternity Hospital Samsun Training and Research Hospital Samsun Turkey Department of Obstetrics and Gynecology Buyuk Anadolu Hospital Samsun Turkey Department of Obstetrics and Gynecology Private Meditech Hospital Ordu Turkey Obstetrics and Gynecology Independent researcher Istanbul Turkey Forensic Medicine Independent researcher Istanbul Turkey Department of Obstetrics and Gynecology Faculty of Medicine Ondokuz Mayis University Samsun Turkey Department of Obstetrics and Gynecology Medical Park Samsun Hospital Samsun Turkey 

出 版 物:《Open Journal of Obstetrics and Gynecology》 (妇产科期刊(英文))

年 卷 期:2020年第10卷第12期

页      面:1677-1685页

学科分类:07[理学] 0701[理学-数学] 070101[理学-基础数学] 

主  题:Pregnancy Asymptomatic Bacteriuria Vitamin D Perinatal Complication Supplementation 

摘      要:Hypothesis: Vitamin D has been considered to play important roles in maintaining pregnancy. Also, this vitamin is considered to regulate immune response and thus may be important for pregnant women also to maintain no-infection of which preterm delivery is especially important. Since vitamin D regulates maternal anti-infection function and sinceAsymptomatic bacteriuria (ASB) causes various adverse outcomes in pregnancy, we hypothesized that maternal serum vitamin D level may be related with the presence/absence of ASB. The present study was an effort to determine this. The study included 215 pregnant women, attended the Ondokuz Mayis University Hospital antenatal care polyclinic, Samsun, Turkey, in the summer for initial visits between 6- and 14-weeks’ gestation. Women with symptoms suggestive of urinary tract infection, a history of antibiotic use within the previous two weeks, ongoing antibiotic therapy or urinary system instrumentation, a diagnosis of vitamin D insufficiency or deficiency, and those taking vitamin D supplements were excluded. Demographic data features of the sampled women were analyzed retrospectively. 10 ml maternal peripheral venous blood samples were collected and the concentrations of 25(OH)D3 in the serum were analyzed. Mid-stream morning urine samples were obtained and analyzed at the microbiology laboratory according to established procedures. ASB was reported if bacteria were present at specified quantitative counts (≥105/su

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