Characterization of Reaction of Primary Amine WithDiketones in Aqueous Solution

作     者：ZHU Qing ZONG Su-san LUO Yan Tony Tang CHEN Xiao-yun William Wang Sam Qiu FENG Shao-guang 

作者机构：Dow Chemical CompanyCore R&DShanghai 201203China The Dow Chemical CompanyCore R&D Analytical SciencesMidlandMI 48674USA 

出 版 物：《光谱学与光谱分析》 (Spectroscopy and Spectral Analysis)

年 卷 期：2020年第40卷第S1期

页      面：245-246页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：Amine Diketone In-situ Raman Reaction monitoring 

摘      要：In this study,the interaction between primary amine and diketones was *** diketones with a general structure of—(CH2C(O)CH2C(O))-X-R(X is C,O or N and R is H and/or alkyl groups)were selected to react with primary amine in aqueous *** reaction was in-situ monitored by Raman technique and the reaction products were identified by FTIR,NMR and *** is found that the reaction products strongly depend on the structures of *** X is nitrogen,the expected Schiff base or its analog can be ***,Schiff base or its analog is not detected if X is C or O,instead,ion pairs or hydrolysis products are formed accordingly,suggesting critical impacts of acidity of CH2 inβ-diketone on the product *** study also shows that in-situ Raman is a powerful technique for reaction monitoring and structure characterization,which is useful for mechanism understanding.