Candida Colonization among Neonates with Low Birth Weight: There Is Much More to Explore

作     者：Wilhelmina Mussa Benard Modest Adolfine Hokororo Florentina Mashuda Vitus Silago Stephen E. Mshana Martha F. Mushi Wilhelmina Mussa;Benard Modest;Adolfine Hokororo;Florentina Mashuda;Vitus Silago;Stephen E. Mshana;Martha F. Mushi

作者机构：Department of Pediatrics and Child Health Weill Bugando School of Medicine Catholic University of Health and Allied Sci-ences Mwanza Tanzania Department of Microbiology and Immunology Weill Bugando School of Medicine Catholic University of Health and Allied Sciences Mwanza Tanzania 

出 版 物：《Open Journal of Pediatrics》 (儿科学期刊（英文）)

年 卷 期：2020年第10卷第4期

页      面：626-634页

学科分类：07[理学] 0701[理学-数学] 070101[理学-基础数学] 

主　　题：Candida Colonization C. albicans C. glabrata Oral 

摘      要：Backgroundand Objectives: Candida colonization in neonates with low birth weight is reported to be the first step for invasive candidiasis. This study was designed to describe the patterns of Candida spp. colonizing neonates with low birth weight in Mwanza, Tanzania to provide baseline information for future studies in this field. Methodology: The hospital based cross sectional study was conducted between January 2019 and April 2019 among neonates with low birth weight. Clinical and social demographic data were collected using interview guide questionnaire. Oral and umbilicalrectal swabs were collected on the first and seventh day of life to assess Candida spp. colonization status. Data were analyzed using STATA version 13 following the study objectives. Results: A total of 320 neonates with median body weight of 1600 [IQR 1000 - 2000] grams were enrolled. Prevalence of Candida spp. colonization on either ora