H. pylori Infection - Basic and Clinical Outcomes

作     者：P.Malfertheiner 

作者机构：Otto-von-GuerickeUniversityDepartmentofGastroenterologyHepatologyandInfectiousDiseasesMagdeburgGermany 

出 版 物：《胃肠病学》 (Chinese Journal of Gastroenterology)

年 卷 期：2000年第5卷第B8期

页      面：63-65页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：H.pylori 传染病 临床作用 炎症 消化性溃疡 胃黏膜 胃癌 

摘      要：H. pylori infection causes invariably chronic inflammation of the gastric mucosa and predisposes for peptic ulcerations in the stomach and duodenum as well as for gastric neoplasias. A subset of patients with chronic gastritis and without additional lesions will develop dyspeptic symptoms, whereas around 80% of all infected may never experience any clinical manifestation. The determinants of different diseases conditions associated with the H. pylori infection are related to the variability of bacterial strains, host genetic factors, and ambiental conditions.