Comparison of two supplemental oxygen methods during gastroscopy with propofol mono-sedation in patients with a normal body mass index
作者机构：Department of AnesthesiologyBeijing Friendship HospitalCapital Medical UniversityBeijing 100050China
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2020年第26卷第43期
页 面：6867-6879页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by“Renfu”Research Fund by Chinese Society of Digestive Endoscopy No.CSDE012017120006
主 题：Gastroscopy Hypoxemia Wei nasal jet tube Nasal cannula Supplemental oxygen Adverse outcomes
摘 要：BACKGROUND Hypoxemia due to respiratory depression and airway obstruction during upper gastrointestinal endoscopy with sedation is a common *** Wei nasal jet tube(WNJT)is a new nasopharyngeal airway with the ability to provide supraglottic jet ventilation and oxygen insufflation via its built-in wall *** available evidence indicates that with a low oxygen flow,compared with nasal cannula,the WNJT does not decrease the occurrence of hypoxemia during upper gastrointestinal endoscopy with propofol *** date,there has been no study assessing the performance of WNJT for supplemental oxygen during upper gastrointestinal endoscopy with sedation when a moderate oxygen flow is *** To determine whether the WNJT performs better than the nasal prongs for the prevention of hypoxemia during gastroscopy with propofol mono-sedation when a moderate oxygen flow is provided in patients with a normal body mass *** This study was performed in 291 patients undergoing elective gastroscopy with propofol *** were randomized into one of two groups to receive either the WNJT(WNJT group,n=147)or the nasal cannula(nasal cannula group,n=144)for supplemental oxygen at a 5-L/min flow during *** lowest SpO2 during gastroscopy was *** primary endpoint was the incidence of hypoxemia or severe hypoxemia during *** The total incidence of hypoxemia and severe hypoxemia during gastroscopy was significantly decreased in the WNJT group compared with the nasal cannula group(P=0.000).The lowest median SpO2 during gastroscopy was significantly higher(98%;interquartile range,97-99)in the WNJT group than in the nasal cannula group(96%;interquartile range,93-98).Epistaxis by device insertion in the WNJT group occurred in 7 patients but stopped naturally without any *** two groups were comparable in terms of the satisfaction of physicians,anesthetists and *** With a moderate oxygen flow,the WNJT
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