Efficacy of Yiqiyangxin Chinese medicine compound combined with cognitive therapy in the treatment of generalized anxiety disorders

作     者：Ting Wang Jing-Yuan Ding Guang-Xing Xu Yu Zeng San-Rong Xiao 

作者机构：School of Psychology and Cognitive ScienceEast China Normal University East China Sanatorium Department of ManagementHainan Medical University 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2012年第5卷第10期

页      面：818-822页

核心收录：

学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

基　　金：supported in part by Research Program in Higher Edueational Intuitions of the Education Department in Hainan(No.Hjsk2011-53) Natural Seientific Research Funds of Hainan in 2011(No.710247) Scientific Research Funds of Hainan Medical University in 2009(No.2009-035) 

主　　题：Yiqiyangxin Chinese medicine Compound Cognitive therapy Generalized anxiety disorder 

摘      要：Objective:To observe the clinical efficacy of Yiqiyangxin Chinese medicine compound combined with cognitive therapy on generalized anxiety ***:A total of 202 generalized anxiety disorders patients were randomly allocated to a control condition(Paroxetine combined with cognitive therapy) or a treatment condition(Yiqiyangxin Chinese medicine compound combined with cognitive therapy).Subsequently,scores of Hamilton Anxiety Scale(HAMA), Zung Self-rating Anxiety Scale(SAS) and blood routine,urine routine,liver function,renal function,electrocardiogram were detected before treatment,3 months,6 months after treatment and 6 months after medicine withdrawal,***:HAMA and SAS scores were significantly reduced in two groups(P0.05).HAMA and SAS scores were significantly increased in two groups(P0.05) after medicine withdrawal,and there were significant differences in HAMA and SAS scores,recurrent disease and adverse reaction(P0.001). The incidence of recurrent disease and adverse reaction in treatment group was *** two groups showed no apparent abnormality in blood routine,urine routine,liver and renal function, and ***:Yiqiyangxin Chinese medicine compound combined with cognitive therapy can significantly reduce the recurrence after medicine withdrawal and is effective on generalized anxiety ***,the incidence of adverse reactions is low. The treatment program is worthy clinic application in the further.