Transarterial chemoembolization combined with radiofrequency ablation in the treatment of hepatocellular carcinomas larger than 5 cm
作者机构：Department of Pain TreatmentTangdu Hospital of the Fourth Military Medical UniversityXi’an 710038China Department of EpidemiologyMinistry of Education Key Lab of Hazard Assessment and Control in Special Operational Environmentthe Fourth Military Medical UniversityXi’an 710032China
出 版 物：《Hepatoma Research》 (肝癌研究（英文版）)
年 卷 期：2019年第5卷第4期
页 面：33-41页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：This study was funded by National Natural Science Foundations of China(81773488 and 8177110260)
主 题：Transarterial chemoembolization radiofrequency ablation hepatocellular carcinoma meta-analysis
摘 要：Aim:This meta-analysis was designed to compare the effectiveness of the combination of transarterial chemoembolization(TACE)and radiofrequency ablation(RFA)*** of TACE alone in hepatocellular carcinoma(HCC)tumors larger than 5 ***:PUBMED,CNKI,and CBM were searched for all related randomized controlled trials(RCTs)up until October 22,*** studies were identified that compared TACE with *** alone for HCC *** response rate,the proportion of patients with either complete or partial shrinkage of tumors,and survival rate were the major evaluation ***:Meta-analysis data revealed that TACE with RFA showed significantly better tumor response rate(risk ratio(RR)=1.452,95%confidence interval(CI):1.308-1.610,P0.001)and 1-year overall survival rate(RR=1.412,95%CI:1.249-1.596,P0.001)than that of TACE alone ***:The data of our study indicates that TACE combined with RFA in the treatment of HCC larger than 5 cm is an effective comprehensive interventional therapy.
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