Neural spike train reconstruction from calcium imaging via a signal-shape composition model

作     者：Yu Shen Tingwei Quan Meng Wang Xiuli Liu Xiaohua Lv Xiaowei Chen Shaoqun Zeng Yu Shen;Tingwei Quan;Meng Wang;Xiuli Liu;Xiaohua Lv;Xiaowei Chen;Shaoqun Zeng

作者机构：Britton Chance Center far Biomedical PhotonicsWuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China MoE Key Laboratory for Biomedical PhotonicsDepartment of Biomedical Engineering.Huazhong University of Science and TechnologyWuhan 430074China Brain Research Center and State Key Laboratory of TraumaBurnsand Combined InjuryThird Military Medical UniversityChongqing 400038China College of Mathematics and EconomicsHubei University of EducationWuhan 430205China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2020年第63卷第12期

页      面：1829-1832页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学] 

基　　金：financially supported by NSFC projects(81327802,61721092) Science Fund for Young and Middle-aged Creative Research Group of the Universities in Hubei Province(T201520) the Director Fund of WNLO 

主　　题：record shape neural 

摘      要：Dear Editor,Since calcium imaging can simultaneously record the calcium signals of several hundred neurons, it has been a powerful tool in measuring the functional activity of neural populations. However, calcium imaging is an indirect measurement of neuronal firing activity, and this technique requires reconstructing the AP trains from the corresponding calcium fluorescence signals of the recorded neurons.