蓝山眼科研究:老龄人群的开角型青光眼和甲状腺疾病

作     者：姜廷帅 Lee A.J RochtchinaE Wang J.J P.Mitchell 

作者机构：University of SydneyDep artment of Ophthalmolog yWestmead HospitalHawkesbury Rd.WestmeadNSW2145Australia 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2005年第1卷第1期

页      面：35-36页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：开角型青光眼 甲状腺疾病 老龄人群 眼科研究 视野检查 甲状腺病 压平眼压计 眼部检查 甲状腺手术 多变量模型 

摘      要：*** assess whether thyroid d isease is indepen-dently associated with open-angle g laucoma (OAG),using history of thyroid disease and curre nt thyroxine *** Blue Mountains Eye Stud y examined 3654persons,aged *** wers collected self-reported history of diagnosis and treatment for thyroid *** examinations included applanation tonome-try,stereoscopic optic disc photography and automated *** was diagnosed from th e presence of matching typical glaucomatous field changes and optic disc cupping,independent of intraocula r *** between thyroid disease(history and treatment )and OAG were assessed in a multivariate *** 324participants(8.9%)reporting history of thyroid disease,147(4.0%)were currently using *** we could not accurately categorize the thyroid disorder for all cases,current use of thyroxine sugg ests a prior hypothyroid *** thyroid dise ase subgroups affected women more frequently than men,P=*** was diagnosed in 108subjects(3.0%)and was more frequent in those reporting past thyroid dise ase(4.6vs2.8%).This relationship was not statistic ally significant after ad-justing for potential confounders,multivariate odds ratio(OR)1.6;95%confidence interval(95%CI 0.9-2.9).OAG was significantly more frequen t,however,in subjects reporting current thyroxine use(6.8vs2.8%),multivariate OR 2.1;95%CI 1.0-4.4,or history of thyroid surgery(6.5vs2.8%),multivariate OR 2.5;95%CI *** population-based study suggests that thyroid disease,indicated by current thyroxine use or past thyroid surgery,could be indepen-dently related to OAG.