Metabolic syndrome and liver disease in the era of bariatric surgery: What you need to know!

作     者：Ioannis A Ziogas Konstantinos Zapsalis Dimitrios Giannis Georgios Tsoulfas 

作者机构：Aristotle University School of MedicineThessaloniki 54124Greece Center for Health Innovations and Outcomes Research(CHIOR)The Feinstein Institute for Medical ResearchManhassetNY 11030United States The First Department of SurgeryAristotle University of ThessalonikiThessaloniki 54124Greece 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2020年第12卷第10期

页      面：709-721页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Metabolic syndrome Bariatric surgery Sleeve gastrectomy Gastric bypass Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Liver transplantation 

摘      要：Metabolic syndrome(MS)is defined as the constellation of obesity,insulin resistance,high serum triglycerides,low high-density lipoprotein cholesterol,and high blood *** increasingly affects more and more people and progressively evolves into a serious issue with widespread healthcare,cost,and quality of life associated *** is associated with increased morbidity and mortality due to cardiovascular or chronic liver *** treatment,which includes diet,exercise,and antidiabetic agents,is the mainstay of treatment,but depends on patient compliance to medical treatment and adherence to lifestyle modification *** surgery has recently emerged as an appropriate alternative treatment with promising longterm *** gastrectomy and Roux-en-Y gastric bypass constitute the most commonly performed procedures and have been proven both cost-effective and safe with low complication *** transplantation is the only definitive treatment for end-stage liver disease and its utilization in patients with nonalcoholic steatohepatitis has increased more than fivefold over the past 15 *** this review,we summarize current state of evidence on the surgical treatment of MS.