Hepatocellular carcinoma Liver Imaging Reporting and Data Systems treatment response assessment: Lessons learned and future directions

作     者：Anum Aslam Richard Kinh Gian Do Avinash Kambadakone Bradley Spieler Frank H Miller Ahmed M Gabr Resmi A Charalel Charles Y Kim David C Madoff Mishal Mendiratta-Lala 

作者机构：Department of RadiologyUniversity of MichiganAnn ArborMI 48019United States Department of RadiologyMemorial Sloan Kettering Cancer CenterNew YorkNY 10065United States Abdominal Imaging and Interventional RadiologyHarvard Medical SchoolMassachusetts General HospitalBostonMA 02114United States Department of RadiologyLouisiana State University Health Sciences CenterNew OrleansLA 70112United States Department of RadiologyNorthwestern University Feinberg School of MedicineNorthwestern UniversityChicagoIL 60611United States Department of Interventional RadiologyOHSU and Tanta UniversityEgyptPortlandOR 97239United States Department of RadiologyWeill Cornell MedicineNew YorkNY 10065United States Department of RadiologyDuke University Medical CenterDuke UniversityDurhamNC 27710United States Department of Radiology and Biomedical ImagingYale School of MedicineNew HavenCT 06520United States School of Medicine1500 East Medical Center DriveUniversity of MichiganAnn ArborMI 48109United States 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2020年第12卷第10期

页      面：738-753页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：National Institute of Health  (PO1 CA59827) 

主　　题：Hepatocellular carcinoma Liver Imaging Reporting and Data Systems Treatment Response Algorithm Locoregional therapy Liver Imaging Reporting and Data Systems Treatment Response equivocal Arterial phase hyper enhancement Stereotactic body radiotherapy 

摘      要：Hepatocellular carcinoma(HCC)is a leading cause of morbidity and mortality worldwide,with rising clinical and economic burden as incidence *** are a multitude of evolving treatment options,including locoregional therapies which can be used alone,in combination with each other,or in combination with systemic *** treatment options have shown to be effective in achieving remission,controlling tumor progression,improving disease free and overall survival in patients who cannot undergo resection and providing a bridge to transplant by debulking tumor burden to downstage *** locoregional therapy(LRT),it is crucial to provide treatment response assessment to guide management and liver transplant ***,Liver Imaging Reporting and Data Systems(LI-RADS)Treatment Response Algorithm(TRA)was created to provide a standardized assessment of HCC following *** TRA provides a step by step approach to evaluate each lesion independently for accurate tumor *** this review,we provide an overview of different locoregional therapies for HCC,describe the expected post treatment imaging appearance following treatment,and review the LI-RADS TRA with guidance for its application in clinical *** to other publications,we will also review emerging literature supporting the use of LI-RADS for assessment of HCC treatment response after LRT.