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Spontaneous Bacterial Peritonitis and Short-Term Prognosis in a Group of Decompensated Cirrhotic Patients in Yaounde: A Cross-Sectional Study

Spontaneous Bacterial Peritonitis and Short-Term Prognosis in a Group of Decompensated Cirrhotic Patients in Yaounde: A Cross-Sectional Study

作     者:Mathurin Pierre Kowo Sylvain Raoul Simeni Njonnou Nelly Karelle Weyou Noubissi Firmin Ankouane Andoulo Gabin Ulrich Kenfack Larissa Pessidjo Djomatcho Hortense Gonsu Kamga Bernadette Ngo Nonga Mathurin Pierre Kowo;Sylvain Raoul Simeni Njonnou;Nelly Karelle Weyou Noubissi;Firmin Ankouane Andoulo;Gabin Ulrich Kenfack;Larissa Pessidjo Djomatcho;Hortense Gonsu Kamga;Bernadette Ngo Nonga

作者机构:Department of Internal Medicine and Specialties Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon Yaounde University Teaching Hospital Yaounde Cameroon Department of Internal Medicine and Specialties Faculty of Medicine and Pharmaceutical Sciences University of Dschang Dschang Cameroon Higher Institute of Medical Technology Yaounde Cameroon Department of Microbiology Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon Department of Surgery Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon 

出 版 物:《Open Journal of Gastroenterology》 (肠胃病学期刊(英文))

年 卷 期:2020年第10卷第8期

页      面:203-213页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Spontaneous Bacterial Peritonitis Decompensated Liver Cirrhosis Sub-Saharan Africa 

摘      要:Introduction: Spontaneous bacterial peritonitis (SBP) is among the most common infections in cirrhotic patients. Data on SBP are rare in Cameroon. This prompted us to carry out this study on patients with decompensated cirrhosis of the liver in Yaounde University Hospital Centre (YUHC). Methods: We carried out a cross-sectional study from December 2015 to June 2016 in three units of YUHC. All patients with decompensated liver cirrhosis were included. Our sampling was consecutive. Diagnosis of cirrhosis was performed, based on clinical, biological and ultrasound criteria. A neutrophil count greater than 250 cell/mm3 in ascites fluid defined an SBP. Data on socio-demography, clinical presentation, and outcomes were collected. Results: We included 34 decompensated cirrhotic patients (15 males). Patients mean age was 57.5±2 years (SBP positive: 48.7 ± 21.3 versus without SBP: 59.8 ± 19.5, p=0.22). SBP diagnosis was made in 6 (17.7%) patients. Compared to patients with decompensated liver cirrhosis and without SBP, positive SBP patients had a higher pulse rate (p=0.002) and respiratory rate (p=0.02). The patients with SBP were more likely to present these other clinical features: pulse rate 100 (RR: 4.2,

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