Prenatal Testing or Screening?

作     者：Evans Mark I. Evans Shara M. Evans Mark I.;Evans Shara M.

作者机构：Fetal Medicine Foundation of AmericaNew YorkNY 10065USA Comprehensive GeneticsNew YorkNY 10065USA Department of Obstetrics&GynecologyIcahn School of Medicine at Mt.SinaiNew YorkNY 10029USA Department of Maternal Child HealthGillings School of Public Health University of North Carolina at Chapel HillChapel HillNY 27599USA 

出 版 物：《Maternal-Fetal Medicine》 (母胎医学杂志（英文）)

年 卷 期：2020年第2卷第4期

页      面：217-222页

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

主　　题：Genetic counseling Prenatal diagnosis Chorionic villus sampling Amniocentesis Array comparative genomic hybridization Noninvasive prenatal testing 

摘      要：Over the past 50 years,the scope and extent of prenatal diagnosis and screening for genetic disorders have improved *** has been a pendulum like swing from testing to screening back and forth as new technologies *** concurrent developments of cell free fetal DNA analysis of maternal blood has dramatically changed patient’s choices towards ***,with the use of array comparative genomic hybridization of fetal DNA that requires diagnostic procedures(Chorionic villus sampling and amniocentesis),much more extensive diagnosis can be *** noninvasive methods can replicate what can be done with diagnostic procedures there still will be aprice to be paidfor opting for the non-invasive methods.