Frequency and Outcome of Meconium Aspiration Syndrome in Babies Born with Meconium-Stained Liquor at Secondary Care Hospital in Pakistan: A Case Series Study

作     者：Abdul Moeed Heeramani Lohana Sarwat Urooj Sheraz Ahmed Khalil Ahmed Khadija Humayun Abdul Moeed;Heeramani Lohana;Sarwat Urooj;Sheraz Ahmed;Khalil Ahmed;Khadija Humayun

作者机构：Aga Khan Maternal and Child Care Centre Hyderabad Pakistan 

出 版 物：《Open Journal of Pediatrics》 (儿科学期刊（英文）)

年 卷 期：2020年第10卷第3期

页      面：381-391页

学科分类：07[理学] 0701[理学-数学] 070101[理学-基础数学] 

主　　题：Meconium Aspiration Syndrome Mortality Neonates Outcome 

摘      要：Background: Meconium aspiration syndrome (MAS) in the newborn is characterized by hypoxia, hypercapnia, and acidosis. MAS is a leading cause of morbidity and mortality in neonates. The primary objective of this study was to estimate the frequency of meconium aspiration syndrome (MAP) in babies born with meconium-stained liquor. The secondary outcome was to estimate the meconium aspiration syndrome;in terms of hospital stay, complications, and mortality. Methods: The study was done at Aga Khan Maternal and Child Care Centre, Hyderabad, Pakistan. Study design was case series and the duration of the study was of 6 months. All patients who fulfilled the inclusion criteria were included in the study after taking informed written consent. A brief history was taken, clinical examination was done and laboratory investigations were sent to the institutional laboratory. Study outcomes were measured from this data i.e. MAS, its complications, mortality, and a number of days in the hospital. Results: A total of 87 babies born with meconium-stained liquor at secondary care hospital were included. A total of 45 patients (52%) were males and 42 patients (48%) were females with a mean gestational age of babies 38.896 ± 1.210 weeks. The mean Apgar score at 5 minutes was 8.896 ± span style=font-family:Verdana;