An Overview on SARS‑CoV‑2(COVID‑19)and Other Human Coronaviruses and Their Detection Capability via Amplification Assay,Chemical Sensing,Biosensing,Immunosensing,and Clinical Assays

作     者：Yasin Orooji Hessamaddin Sohrabi Nima Hemmat Fatemeh Oroojalian Behzad Baradaran Ahad Mokhtarzadeh Mohamad Mohaghegh Hassan Karimi‑Maleh Yasin Orooji;Hessamaddin Sohrabi;Nima Hemmat;Fatemeh Oroojalian;Behzad Baradaran;Ahad Mokhtarzadeh;Mohamad Mohaghegh;Hassan Karimi?Maleh

作者机构：College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037People’s Republic of China Jiangsu Co‑Innovation Center for Efficient Processing and Utilization of Forest ResourcesNanjing Forestry UniversityNanjing 210037People’s Republic of China Department of Analytical ChemistryFaculty of ChemistryUniversity of TabrizTabriz 51666‑16471Iran Immunology Research CenterTabriz University of Medical SciencesTabrizIran Department of Advanced Sciences and Technologies in MedicineSchool of MedicineNorth Khorasan University of Medical SciencesBojnurdIran Department of NanobiotechnologySchool of Biological SciencesTarbiat Modares UniversityTehranIran Department of Chemical EngineeringLaboratory of NanotechnologyQuchan University of TechnologyQuchanIslamic Republic of Iran School of Resources and EnvironmentUniversity of Electronic Science and Technology of ChinaXiyuan AveChengdu 611731People’s Republic of China Department of Chemical SciencesUniversity of JohannesburgDoornfontein CampusPO Box 17011Johannesburg 2028South Africa 

出 版 物：《Nano-Micro Letters》 (纳微快报（英文版）)

年 卷 期：2021年第13卷第1期

页      面：337-366页

核心收录：

学科分类：0808[工学-电气工程] 0809[工学-电子科学与技术（可授工学、理学学位）] 0817[工学-化学工程与技术] 080202[工学-机械电子工程] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 0805[工学-材料科学与工程（可授工学、理学学位）] 0802[工学-机械工程] 0702[理学-物理学] 10[医学] 

基　　金：Nanjing Forestry University[Grant Nos.163020139,164020818,163020217 and 16302023] National Natural Science Foundation of China(5201101466) 

主　　题：ELISA qRT-PCR Sensing assay Apta assay Amplification assay 

摘      要：A novel coronavirus of zoonotic origin(SARSCoV-2)has recently been recognized in patients with acute respiratory ***-19 causative agent is structurally and genetically similar to SARS and bat SARS-like *** drastic increase in the number of coronavirus and its genome sequence have given us an unprecedented opportunity to perform bioinformatics and genomics analysis on this class of *** tests like PCR and ELISA for rapid detection of this virus are urgently needed for early identification of infected ***,these techniques are expensive and not readily available for point-of-care(POC)***,lack of any rapid,available,and reliable POC detection method gives rise to the progression of COVID-19 as a horrible global *** solve the negative features of clinical investigation,we provide a brief introduction of the general features of coronaviruses and describe various amplification assays,sensing,biosensing,immunosensing,and aptasensing for the determination of various groups of coronaviruses applied as a template for the detection of *** sensing and biosensing techniques developed for the determination of various classes of coronaviruses are useful to recognize the newly immerged coronavirus,i.e.,***,the introduction of sensing and biosensing methods sheds light on the way of designing a proper screening system to detect the virus at the early stage of infection to tranquilize the speed and vastity of *** other approaches investigated among molecular approaches and PCR or recognition of viral diseases,LAMP-based methods and LFAs are of great importance for their numerous benefits,which can be helpful to design a universal platform for detection of future emerging pathogenic viruses.