An exclusive fine-needle biopsy approach to sampling solid lesions under EUS guidance:a prospective cohort study

作     者：Lindsey M.Temnykh Mahmoud A.Rahal Zahra Zia Mohammad A.Al-Haddad 

作者机构：Department of Internal MedicineIndiana University School of MedicineIndianapolisINUSA Division of Gastroenterology and HepatologyDepartment of Internal MedicineIndiana University School of MedicineIndianapolisINUSA 

出 版 物：《Gastroenterology Report》 (胃肠病学报道（英文）)

年 卷 期：2020年第8卷第5期

页      面：349-354,I0001页

核心收录：

学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

主　　题：endoscopic ultrasound fine-needle biopsy fine-needle aspiration pancreatic tumors 

摘      要：Background Endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB)is increasingly utilized to enhance the cytological yield of sampling solid lesions,but its superiority over existing fine-needle aspiration(FNA)platforms has not been clearly *** aim of our study was to compare the diagnostic accuracy and procedural outcomes of FNB using a new Franseen-tip needle to that of a traditional FNA in sampling solid lesions under EUS *** Consecutive patients with solid lesions referred for EUS-FNB sampling were ***-related outcomes were collected prospectively including patient demographics,number of passes performed,diagnostic sample adequacy,adverse events,and recovery *** Acquire needle was used to sample all lesions in the study *** EUSFNA procedures performed to sample solid lesions using the Expect needle were utilized as *** There were 180 patients undergoing EUS-FNB compared to 183 patients undergoing EUS-FNA procedures for solidlesion *** procedure time was significantly shorter in patients who underwent FNB compared to FNA(mean:37.4 vs 44.9 minutes,P0.001).Significantly fewer passes were performed in the FNB cohort compared to the FNA group(mean:2.9 vs 3.8,P0.001).The cytologic diagnostic yield was significantly higher in the FNB group compared to the FNA group(98.3%vs 90.2%,P=0.003).No significant difference in the incidence of adverse events was observed between the FNB and FNA groups(1.1%vs 0.5%,P=0.564).Conclusions An FNB-exclusive approach to sampling solid lesions under EUS guidance is safe and feasible,and may result in fewer overall passes,shorter procedure time,and improved diagnostic *** may replace FNA as the primary sampling modality of choice in all solid lesions.