Advances in Single Nucleotide Polymorphisms of Vitamin D Metabolic Pathway Genes and Respiratory Diseases
作者机构：First Clinical College of Hainan Medical UniversityHaikouHainan570100China School of Public HealthHainan Medical UniversityHaikouHainan570100China School of Tropical Medicine and LaboratoryHainan Medical UniversityHaikouHainan570100China
出 版 物：《Journal of Advances in Medicine Science》 (医学科学进展杂志（英文）)
年 卷 期：2020年第3卷第3期
页 面：25-30页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：National College Student Innovation and Entrepreneurship Training Project(Project No.:202011810001)
主 题：Vitamin D metabolic pathway genes Single nucleotide polymorphisms Respiratory diseases
摘 要：Vitamin D is a fat-soluble *** is an essential vitamin for human *** has a classical effect on regulating calcium and phosphorus *** in cellular and humoral immune processes by regulating the growth,differentiation and metabolism of immune cells.A large number of studies in recent years have shown that vitamin D deficiency increases the incidence of respiratory *** diseases mainly include bronchial asthma,chronic obstructive pulmonary disease,tuberculosis,acute upper respiratory tract infection and *** D metabolic pathway genes play a very important regulatory role in the transformation of vitamin D into active vitamin D,including CYP2R1,CYP27B1,CYP24A1,VDBP,VDR five *** polymorphism of genes is the molecular basis of individual differences and disease ***,this paper summarizes the research on single nucleotide polymorphism of vitamin D metabolic pathway gene and respiratory *** order to provide a new idea for future treatment.
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