Utilization of Swertia chirayita Plant Extracts for Management of Diabetes and Associated Disorders: Present Status, Future Prospects and Limitations
作者机构：Department of BiotechnologyKarunya Institute of Technology and SciencesCoimbatoreTamil Nadu 641114India Department of MicrobiologyLovely Professional UniversityPhagwaraPunjab 144411India Biotechnology DepartmentVignan Foundation for Science Technology and ResearchGunturAndhra Pradesh 522213India National Dong Hwa UniversityDepartment of Life SciencesHualienChina Department of Chemical EngineeringVSB Engineering CollegeKarurTamil Nadu 639111India
出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)
年 卷 期：2020年第10卷第6期
页 面：431-443页
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100602[医学-中西医结合临床] 10[医学]
基 金：KITS
主 题：Swertia chirayita Diabetes Phytochemicals Conservation
摘 要：Diabetes mellitus is referred as common metabolic abnormalities characterized as hyperglycemia,mainly caused due to insufficient production of insulin at cellular level or/and defects in insulin *** an endocrine disorder is responsible for serious health problems and its worldwide prevalence is rapidly *** management of diabetes by oral administration of drugs without creating any side effects is still considered a challenging task and increasing cost of con-ventional medicine in developing countries is another matter of *** address these issues,traditional preparations of herbal plant extracts in the form of medicines already gained immense *** chirayita is one among such plants which is known for its hypoglycemic *** chemical constituents with promising pharmacological properties have been identified from such plant extracts but still,such compounds have not been well characterized,specifically against human ***,more research efforts are necessitated to understand exact mechanism of such compounds and to develop overall safety of such plant *** review clearly represents antidiabetic properties of Swertia chirayita extract,strategies to be taken to strengthen its safety application on humans and biotechnological interventions that ensure conservation of such endangered species to promote its future application in modern medicine.
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