Extremely rare case of successful treatment of metastatic ovarian undifferentiated carcinoma with high-dose combination cytotoxic chemotherapy: A case report
作者机构：Department of Premedical CourseChosun University School of MedicineGwngju 505717South Korea Department of Internal MedicineHemato-oncologyChosun University HospitalGwangju 505717South Korea Department of PathologyChosun University HospitalGwangju 505717South Korea
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2020年第8卷第19期
页 面：4488-4493页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：the National Research Foundation of Korea,funded by the Ministry of Science,ICT,and Future Planning,No.NRF-2017R1D1A1B04031741 and grants from the Chosun University Hospital,No.2019
主 题：Ovarian undifferentiated carcinoma Sarcomatoid change Chemotherapy Etoposide,ifosfamide,cisplatin Case report
摘 要：BACKGROUND Ovarian undifferentiated carcinomas are significantly rare and have an aggressive clinical *** resection is the only curative treatment in early-stage ovarian undifferentiated carcinomas that has a favorable *** case of recurrent and metastatic disease,palliative chemotherapy is the only available ***,the effectiveness of standard chemotherapy regimen is not well-known,specifically in the case of extra-ovarian *** report an ovarian undifferentiated carcinoma of recurrent and inoperable advanced stage that was successfully treated with high-dose combination *** SUMMARY A 52-year-old woman presented with a 1-mo history of right lower quadrant and epigastric pain.A computed tomography(CT)scan of the abdomen revealed a multicystic mass with extensive internal necrosis of the right ovary without evidence of metastatic disease.A total hysterectomy with bilateral salpingooophorectomy and omentectomy was performed,but the surgery had a positive resection ***,it was diagnosed as ovarian undifferentiated carcinoma with sarcomatoid *** adjuvant chemotherapy was planned,it was delayed for 6 wk because of postoperative recovery,and the patient complained of abdominal pain.A CT scan and positron emission tomography-CT revealed a huge mass with multiple nodules in the pelvic cavity and para-aortic lymph node *** of standard therapy such as paclitaxel and platinum,combined chemotherapy with etoposide,ifosfamide,and cisplatin was *** patient experienced no recurrence for 5 *** This is a case of metastatic ovarian undifferentiated carcinoma with sarcomatoid change that was successfully treated with high-dose combination cytotoxic chemotherapy.
维普期刊数据库