Role of dental plaque,saliva and periodontal disease in Helicobacter pylori infection

作     者：Pradeep S Anand Kavitha P Kamath Sukumaran Anil 

作者机构：Department of PeriodonticsPeople’s College of Dental Sciences and Research CentreBhopalMadhya Pradesh 462037India Department of Oral PathologyPeople’s Dental AcademyBhopalMadhya Pradesh 462037India Department of Periodontics and Community DentistryCollege of DentistryKing Saud UniversityRiyadh 11545Saudi Arabia 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第19期

页      面：5639-5653页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1003[医学-口腔医学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 100302[医学-口腔临床医学] 10[医学] 

主　　题：Helicobacter pylori Dental plaque Saliva Oral cavity Periodontitis Periodontal therapy 

摘      要：Helicobacter pylori (H. pylori) infection is one of the most common bacterial infections in humans. Although H. pylori may be detected in the stomach of approximately half of the world’s population, the mechanisms of transmission of the microorganism from individual to individual are not yet clear. Transmission of H. pylori could occur through iatrogenic, fecal-oral, and oral-oral routes, and through food and water. The microorganism may be transmitted orally and has been detected in dental plaque and saliva. However, the role of the oral cavity in the transmission and recurrence of H. pylori infection has been the subject of debate. A large number of studies investigating the role of oral hygiene and periodontal disease in H. pylori infection have varied significantly in terms of their methodology and sample population, resulting in a wide variation in the reported results. Nevertheless, recent studies have not only shown that the microorganism can be detected fairly consistently from the oral cavity but also demonstrated that the chances of recurrence of H. pylori infection is more likely among patients who harbor the organism in the oral cavity. Furthermore, initial results from clinical trials have shown that H. pylori-positive dyspeptic patients may benefit from periodontal therapy. This paper attempts to review the current body of evidence regarding the role of dental plaque, saliva, and periodontal disease in H. pylori infection.