Mn(Ⅲ)-mediated radical reaction of 2-isocyano-6-alkenyl(alkynyl)benzonitriles with arylboronic acids:Synthesis of pyrroloisoquinoline derivatives

作     者：Pei Xu Yi-Ming Zhu Xin-Yu Liu Xiao-Zhou Zhou Shun-Yi Wang Shun-Jun Ji Pei Xu;Yi-Ming Zhu;Xin-Yu Liu;Xiao-Zhou Zhou;Shun-Yi Wang;Shun-Jun Ji

作者机构：Key Laboratory of Organic Synthesis of Jiangsu ProvinceCollege of ChemistryChemical Engineering and Materials Science&Collaborative Innovation Center of Suzhou Nano Science and TechnologySoochow UniversitySuzhou 215123China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2021年第32卷第1期

页      面：413-416页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the National Natural Science Foundation of China(Nos.21971174,21772137,21542015 and 21672157) PAPD,the Project of Scientific and Technologic Infrastructure of Suzhou(No.SZS201708) the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions(No.16KJA150002) Soochow University for financial support 

主　　题：2-Isocyano-6-alkenyl(alkynyl)benzonitriles Arylboronic acids Pyrroloisoquinoline derivatives Radical reaction 

摘      要：A Mn(Ⅲ) mediated radical reaction of new designed multi-functionalized 2-isocyano-6-alkenyl(alkynyl)benzonitriles with arylboronic acids has been *** reaction provides a method for the synthesis of pyrroloisoquinoline derivatives through the formation of two C-C bonds and one C-N bond via radical cascade cyclization in one step.