Research progress on metabolomics of diabetic retinopathy
作者机构：State Key Laboratory of Component-Based Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin 301617China Engineering Research Center of Modern Chinese Medicine Discovery and Preparation TechniqueMinistry of EducationTianjin University of Traditional Chinese MedicineTianjin 301617China School of Integrative MedicineTianjin University of Traditional Chinese MedicineTianjin 301617China College of Traditional Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin 301617China Central Hospital of Zhuze Town of Liyang CityLiyang 213351China.
出 版 物：《Asian Toxicology Research》
年 卷 期：2020年第2卷第3期
页 面：122-126页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Metabolomics Diabetes mellitus Diabetic retinopathy Biomarkers Research progress
摘 要：Diabetic retinopathy is the most common microvascular complication of diabetes mellitus and the primary reason for blindness all over the world,which is a lesion of blood vessels,neurons,and glial cells that constitute the complete structure of the *** may have vision loss and irreversible *** the increase in the number of diabetes mellitus patients and the extension of lifespan,the incidence rate gradually *** clinical diagnosis of diabetic retinopathy mainly relies on regular examinations of ocular fundus and subjective patient descriptions,and once diabetic retinopathy is diagnosed,it is difficult to *** is necessary to find the early markers of diabetic *** this paper,data collection,data analysis of metabolomics and its research progress in diabetic retinopathy are summarized and *** recent years,metabolomics has made some progress in the discovery of biomarkers,the exploration of pathogenesis,and the evaluation of diabetic retinopathyug efficacy of diabetic ***,there are currently few metabolomics studies on the progression of diabetes mellitus to diabetic *** determination of diabetic retinopathy-related specific biomarkers also requires data which a large number of animal experiments and clinical trials *** addition,despite the rapid development of metabolomics as an emerging discipline,there are still some problems,which need to be further improved in terms of analysis technology,data acquisition and data *** general,there is still a lot of work to be done to apply metabolomics to clinical work.
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