Highly Site-selective Electrooxidation Providing Facile Entries to Functionalized Aromatic Acetals
作者机构：Key Laboratory of Molecule Synthesis and Function Discovery(Fujian Province University)College of ChemistryFuzhou UniversityFuzhou 350108P.R.China
出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)
年 卷 期：2020年第36卷第4期
页 面：723-724页
核心收录：
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金：Supported by the Student Research Training Program of Fuzhou University China(No.202010386007)
摘 要：Given the fact that aldehydes are among the most fundamental and versatile building blocks in organic syn thesis,the development of highly efficient and selective methods for their preparation,especially for those delicatelk functionalized ones remains sigmificant *** address such an issue,Xu and co-workers have recently reported an elegant electrochemical approach realizing the highly regioselective oxidation of functionalized methyl aromatic hydrocarbons towards the desired aromatic acetals without the use of any chemical oxidants or transition metal catalysts These acetals can be then conveniently converted into corresponding structurally diverse aldehydes via *** addition,the synthetic practicability of current method was further highlighted as the key step in the preparation of the antihypertensive drug *** work has been published in the Nature Communications and can be reached at https://***/10.1038/s41467-020-16519-8.
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