Andrographolide as a potent and promising antiviral agent

作     者：Latif Reshi Wang Chi-Yong Latif Reshi;Wang Chi-Yong

作者机构：Department of Veterinary MedicineCollege of Veterinaiy MedicineNational Chung Hsing UniversityTaichung 40227TaiwanChina 

出 版 物：《Chinese Journal of Natural Medicines》 (中国天然药物（英文版）)

年 卷 期：2020年第18卷第10期

页      面：760-769页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：the Postdoctoral Grant(No.MOST 106-2313-B-005-053-MY3) 

主　　题：Andrographolide Vaccines Antiviral drugs Antimicrobial Life cycle Viral infection 

摘      要：Andrographolide is a labdane diterpenoid extracted and purified from the aerial parts of plants belonging to genus Andrographis(Acanthaceae).The research has shown the plant based compound is low cytotoxic,having antimicrobial,anti-cancer,antiviral and anti-parasitic *** both prevent spread as well as transmission of virus to neighboring cells by interfering with different cell signaling *** addition to its medicinal value,plant has been found having nutritional *** being cost effective,easy availability and having nutritional value as a natural supplement,can be used to improve the quality of life in countries having low standard of *** to the limited number of effective vaccines,the plant-based antiviral drugs have provided considerable hope for fighting against the viral *** plant-derived compound when produced in large quantities is cost effective with low cytotoxic ***,much deep insight research at the molecular level is needed to develop the molecules against the viral *** paper aims to highlight the antiviral role of Andrographolide that can made significant contributions toward the improvement of human health and will also summarize the current status and future strategies concerning the therapeutic applications of Andrographolide to combat different viral disease in humans.