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文献详情 >Correction to: Novel and poten... 收藏

Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2

作     者:Rui Xiong Leike Zhang Shiliang Li Yuan Sun Minyi Ding Yong Wang Yongliang Zhao Yan Wu Weijuan Shang Xiaming Jiang Jiwei Shan Zihao Shen Yi Tong Liuxin Xu Yu Chen Yingle Liu Gang Zou Dimitri Lavillete Zhenjiang Zhao Rui Wang Lili Zhu Gengfu Xiao Ke Lan Honglin Li Ke Xu 

作者机构:State Key Laboratory of VirologyCollege of Life SciencesWuhan UniversityWuhan 430072China Shanghai Key Laboratory of New Drug DesignState Key Laboratory of Bioreactor EngineeringSchool of PharmacyEast China University of Science and TechnologyShanghai 200237China State Key Laboratory of VirologyWuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan 430071China CAS Key Laboratory of Molecular Virology and ImmunologyInstitut Pasteur of ShanghaiUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China 

出 版 物:《Protein & Cell》 (蛋白质与细胞(英文版))

年 卷 期:2021年第12卷第1期

页      面:76-80页

核心收录:

学科分类:0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100705[医学-微生物与生化药学] 100706[医学-药理学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 100602[医学-中西医结合临床] 10[医学] 

主  题:Figure discovery ODH 

摘      要:Figure *** of novel and potent DHODHi and their anti-influenza A virus activities.(A)The discovery and design of S312 and *** detailed descriptions of the discovery workflow are in *** analysis of S312(B)and S416(C).Thermodynamic analysis of the binding of S312 and S416 to DHODH was carried out at 25 C on a MicroCal iTC200 *** analysis of the binding of S312 and S416 to DHODH was performed with a Biacore T200 instrument.

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