Biomechanical research into lamina cribrosa in glaucoma
Biomechanical research into lamina cribrosa in glaucoma作者机构:State Key Laboratory of Nonlinear Mechanics and Beijing Key Laboratory of Engineered Construction and Mechanobiology Institute of MechanicsChinese Academy of Sciences School of Engineering Science University of Chinese Academy of Sciences
出 版 物:《National Science Review》 (国家科学评论(英文版))
年 卷 期:2020年第7卷第8期
页 面:1277-1279页
核心收录:
学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 1002[医学-临床医学] 08[工学] 100212[医学-眼科学] 0836[工学-生物工程] 10[医学]
基 金:supported by the NSFC Basic Science Center Program for ‘Multiscale Problems in Nonlinear Mechanics’(11988102) the National Natural Science Foundation of China (11972041and 11902327) the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB22040102)
摘 要:Glaucoma, a leading cause of irreversible blindness, poses a considerable public health challenge and burden. Mechanical models of the lamina cribrosa under elevated intraocular pressure at different scales, contributing significantly to uncovering the glaucomatous pathogenesis, are discussed. Meanwhile, the open issues and avenues for further development are highlighted.