Primary research on neoplasm needle track implantation metastasis after radioactive seeds implantation and preventive measures

作     者：Juan Wang Weihong Gong Huige Fan Aixia Sui Na Zhao Yongqing Shen 

作者机构：Department of Oncology Hebei Provincial People＇s Hospital Shijiazhuang 050051 China 

出 版 物：《The Chinese-German Journal of Clinical Oncology》 (中德临床肿瘤学杂志（英文版）)

年 卷 期：2007年第6卷第4期

页      面：405-407页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：tumors radioactive seeds puncture neoplasm implantation/metastasis preventions 

摘      要：Objective:To observe the possibility of neoplasm needle track implantation after radioactive seeds implantation and seek preventive measures to avoid ***:Superficial tissue of 250 seeding needle cores and 250 stylophores employed in neoplasm radioactive seeds implantation was smeared on slides to search for tumor *** patients received chemotherapy or endocrine therapy after *** B-mode or computer tomography(CT)was performed at 10th day,30th day,60th day,and 180th day post operation to detect neoplasm implantation metastasis through needle tracks. Results:Positive cells were found on 13 of 250(5.20%)cores,and 7 of 250(2.80%)*** difference was not sta- tistically significant(P0.05).The positive cells frequency of needles those traversed distance less than 3 cm in normal tissue was 6.19%(13/210),while the frequency of the others those traversed longer distance in normal tissue was 2.41%(7/290). The positive cells frequency of needles traversing different distances in normal tissues is significantly different(P0.05).No neoplasm was detected through needle tracks by ultrasound B-mode or CT in 180 days after ***:Tumor cells could ablate into the needle track during radioactive seed *** preventive measures,such as optimization of pre-operation and intra-operation treatment plan,chemotherapy or endocrine therapy after operation,may be beneficial to avoid the implantation metastasis of neoplasm in seeding needle tracks.