Characteristics of Surface Plasmon Resonance Imaging lnterferometer

作     者：Wei Xing Deng Yan Liu Fangfang Yu Xinglong 

作者机构：Dept. of Precision Instruments Tsinghua University Beijing 100084 China 

出 版 物：《稀有金属材料与工程》 (Rare Metal Materials and Engineering)

年 卷 期：2006年第35卷第A3期

页      面：595-599页

核心收录：

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

主　　题：surface plasmon resonance(SPR) detection range linearity sensitivity resolution 

摘      要：In recent life science research,identifying and characterizing entire biomolecular interaction networks is prerequisite to understanding cellular processes on a molecular and biophysical level.A surface plasmon resonance (SPR) imaging interferometer based on spatial phase modulation detection is presented to meet this *** this method,the SPR sensing chip surface is illuminated with collimated parallel light beam,and a Wollaston prism is introduced into the reflected light path to produce the interference of polarized light reflected from SPR sensing *** of biomolecular interactions can be obtained by extracting the phase change from the SPR interference *** our interferometer,we made experiments on a series concentration of NaCl solutions to investigate its detection range,linearity,sensitivity and *** results indicate that the SPR imaging interferometer is mainly sufficient for biomolecular interaction detection.