Effectiveness and safety of traditional Chinese medical therapy for cancer-related fatigue: a systematic review and Meta-analysis of randomized controlled trials

作     者：Zhao Yueyang Wang Sumei Li Jinhua Zhou Yushu Wu Wanyin Swei Sunny Hann Zhao Yueyang;Wang Sumei;Li Jinhua;Zhou Yushu;Wu Wanyin;Swei Sunny Hann

作者机构：Department of HematologyDepartment of Medical OncologyLaboratory of Tumor BiologyGuangdong Provincial Hospital of Chinese MedicineThe Second Clinical Medical CollegeGuangzhou University of Chinese MedicineGuangzhouGuangdong Province 510120China 

出 版 物：《Journal of Traditional Chinese Medicine》 (中医杂志（英文版）)

年 卷 期：2020年第40卷第5期

页      面：738-748页

核心收录：

学科分类：1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Supported by Grants from the Natural Science Foundation of China(No.81903991,No.81974543) the Natural Science Foundation of Guangdong Province(No.2017A030310326,No.2019A1515011362) the Guangzhou science and technology plan project(No.201804010149,No.202002030155) the Chinese medicine science and technology research project of Guangdong Provincial Hospital of Chinese Medicine(No.YN2019MJ09) the Major Research Projects in First-class Disciplines of Guangzhou University of Chinese Medicine(No.A1260619111001) the Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome(No.ZH2020KF03) 

主　　题：Neoplasms Fatigue Medicine,Chinese Traditional Quality of life Systematic review Randomized clinical trial 

摘      要：OBJECTIVE:To assess the effectiveness and safety of traditional Chinese medical therapy for cancer-related ***:We systematically searched eight electronic databases up to June 2017 for randomized clinical trials of traditional Chinese medical therapy for cancer-related *** authors independently extracted data and assessed the risk bias of the included trials using the Cochrane *** were analyzed by Rev Man 5.2 ***:A total of 23 trials involving 1832 participants identified with cancer-related fatigue were *** trials reported a beneficial effect of traditional Chinese medical therapy on cancer-related *** pooling the data from Chinese herbal medicine therapy and acupuncture or moxibustion therapy,respectively,significant differences were found between experimental groups and control *** improvement rates showed significant differences between traditional Chinese medical therapy and control groups[odds ratio(OR),7.62;95%confidence interval(CI),3.75-15.49;P0.00001;and OR,3.78;95%CI,2.29-6.23;P0.00001).Fatigue change scores also showed significant differences between the two groups(mean difference,-0.91;95%CI,-1.16 to-0.65;P0.00001).Eleven trials demonstrated that traditional Chinese medical therapy improved the quality of life of cancer *** severe adverse effects occurred in traditional Chinese medical therapy ***:Meta-analysis showed that Chinese medical therapy seems to be effective and safe in the treatment of cancer-related fatigue.