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Hepatitis A:Epidemiology and prevention in developing countries

Hepatitis A:Epidemiology and prevention in developing countries

作     者:Elisabetta Franco Cristina Meleleo Laura Serino Debora Sorbara Laura Zaratti 

作者机构:Department of Public HealthUniversity Tor Vergata Specialization School for Hygiene and Preventive Medicine University Tor Vergata 

出 版 物:《World Journal of Hepatology》 (世界肝病学杂志(英文版)(电子版))

年 卷 期:2012年第4卷第3期

页      面:68-73页

学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主  题:Hepatitis A Developing countries Endemic-ity Seroprevalence Vaccine 

摘      要:Hepatitis A is the most common form of acute viral hepatitis in the *** geographical differences in endemicity of hepatitis A are closely related to hygienic and sanitary conditions and other indicators of the level of socioeconomic *** anti-hepatitis A virus(HAV)seroprevalence rate is presently decreasing in many parts of the world,but in less developed regions and in several developing countries,HAV infection is still very common in the first years of life and seroprev-alence rates approach 100%.In areas of intermediate endemicity,the delay in the exposure to the virus has generated a huge number of susceptible adolescents and adults and significantly increased the average age at *** the severity of disease increases with age,this has led to outbreaks of hepatitis *** factors contribute to the decline of the infection rate,including rising socioeconomic levels,increased access to clean water and the availability of a hepatitis A vaccine that was developed in the *** populations with a high proportion of susceptible adults,implementing vaccination programs may be *** this report,we review available epidemiological data and implementation of vaccination strategies,particularly focusing on developing countries.

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