Radioactive ^125I seed implantation for locally advanced pancreatic cancer:A retrospective analysis of 50 cases
作者机构：Second Department of Hepatobiliary SurgeryChinese PLA General HospitalBeijing 100853China
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2020年第8卷第17期
页 面：3743-3750页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Pancreatic cancer Radioactive^125I seeds Radiotherapy Permanent implantation
摘 要：BACKGROUND Pancreatic cancer is one of the common malignant tumors of the digestive system,and radical resection is the first choice of treatment for pancreatic *** patients with locally advanced pancreatic cancer cannot be treated in time and effectively,their disease often develops rapidly and their survival period is very *** To evaluate the therapeutic effect of ^125I seed implantation in patients with locally advanced pancreatic *** The demographics and perioperative outcomes of a consecutive series of patients who underwent ^125I seed implantation to treat locally advanced pancreatic cancer between January 1,2017 and June 30,2019 were retrospectively *** to the results of preoperative computed tomography or magnetic resonance imaging,the treatment planning system was used to determine the area and number of ^125I seeds *** the operation,^125I seeds were implanted into the tumor under the guidance of intraoperative ultrasound,with a spacing of 1.5 cm and a row spacing of 1.5 *** patients with obstructive jaundice and digestive tract obstruction,choledochojejunostomy and gastroenterostomy were performed *** operation,the patients were divided into a non-chemotherapy group and a chemotherapy group that received gemcitabine combined with albumin-bound paclitaxel *** Among the 50 patients,there were 29 males and 21 females,with a mean age of 56.9±9.8 *** main reason for the failure of radical resection was superior mesenteric artery invasion(37,74%),followed by superior mesenteric vein invasion(33,66%).Twenty-one(62%)patients underwent palliative surgery and postoperative pain relief occurred in 40(80%)*** estimated blood loss in operation was 107.4±115.3 mL and none of the patient received blood *** postoperative hospital stay was 7.5±4.2 d;one patient had biliary fistula and three had pancreatic fistula,all of whom recovered after conservative treatment
维普期刊数据库