Efficacy and safety of high-dose ultrasound cyclo-plasty procedure in refractory glaucoma

作     者：He-Ting Liu Qing Zhang Zheng-Xuan Jiang Yu-Xin Xu Qian-Qian Wan Li-Ming Tao 

作者机构：Department of Ophthalmologythe Second Affiliated Hospital of Anhui Medical UniversityHefei 230601Anhui ProvinceChina 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2020年第13卷第9期

页      面：1391-1396页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：Supported by the Anhui Medical University Research Fund Project(No.2018xkj042) the Second Hospital of Anhui Medical University Incubation Project of NSFC(No.2019GQFY04) Science and Technology New Star Training Project(No.2018KA08) 

主　　题：ultrasound cyclo-plasty cyclodestruction intraocular pressure reduction glaucoma 

摘      要：AIM:To evaluate the efficacy and safety of high-dose ultrasound cyclo-plasty(UCP)for the treatment of refractory glaucoma in Chinese ***:In this 6-month retrospective study,37 eyes of 37 patients suffering from severe glaucoma with uncontrolled intraocular pressure(IOP)of≥21 mm Hg underwent 8-s ultrasonic cyclocoagulation with ten active piezoelectric elements.A complete ophthalmic examination was performed before and at 1 d,1,3,6 mo after *** success was defined as IOP reduction from baseline≥20%and IOP≥5 mm Hg without adding new glaucoma medication compare to baseline at the 6-month follow-up *** addition to mean IOP at each followup visit,medications used and complications were also detected and compared to ***:After UCP procedure,the mean IOP was significantly reduced(P0.01)from the preoperative 44.1±11.9 mm Hgto postoperative 26.7±11.8 mm Hg at 3 mo,and 30.4±14.5 mm Hg at 6 *** overall mean IOP reductions achieved at 3 and 6 mo were 39%and 31%compared to baseline ***-one percent of patients responded well to UCP treatment with a mean IOP reduction of 48%at 3 mo and 42%at 6 *** pain in most of patients were *** serious intraoperative or postoperative complications ***:High-dose UCP treatment is an effective and safe procedure to reduce IOP in Chinese patients with severe glaucoma.