Intravascular lymphoma with hypopituitarism: A case report
作者机构：Department of General Internal MedicineShonan Kamakura General HospitalKanagawa 247-8533Japan Department of HistopathologyShonan Kamakura General HospitalKanagawa 247-8533Japan Department of HematologyShonan Kamakura General HospitalKanagawa 247-8533Japan
出 版 物：《World Journal of Clinical Oncology》 (世界临床肿瘤学杂志（英文版）)
年 卷 期：2020年第11卷第8期
页 面：673-678页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Intravascular lymphoma Random skin biopsy Hypopituitarism General internal medicine Tingling Pancytopenia Case report
摘 要：BACKGROUND Intravascular lymphoma(IVL)is a rare subtype of lymphoma involving the growth of lymphoma cells within the vessel lumina without *** of various modes of presentation and its rarity,IVL is often diagnosed ***,we report a case of intravascular B-cell lymphoma with hypopituitarism,an extremely rare complication,that was successfully treated with *** SUMMARY An 80-year-old Japanese woman presented with a 7-mo history of a tingling sensation in the lower *** also presented with various other symptoms such as pancytopenia,high fever daily,and unconsciousness with *** the doctor who previously treated her diagnosed hypoglycemia as being due to hypopituitarism,the cause of the other symptoms remained uncertain despite a 7-mo evaluation *** performed bone marrow aspiration to evaluate pancytopenia and found that she had hemophagocytic lymphohistiocytosis(HLH).On the basis of a random skin biopsy for assessing the cause of HLH,she was diagnosed with intravascular B-cell *** and hypopituitarism were considered secondary to *** her clinical findings matched the presentations of *** was immediately treated with chemotherapy and achieved complete *** was relapse free two years after *** IVL should be included in the differential diagnosis of hypopituitarism,which although life-threatening,is treatable through prompt diagnosis and appropriate chemotherapy.
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