Epidemiologic and clinical characteristics of 42 deaths caused by SARS-CoV-2 infection in Wuhan, China: A retrospective study

作     者：Nan Zhang Haochen Yao Dong Zhang Jiahui Pan Ejun Peng Juanjuan Huang Yingli Zhang Xiaoming Xu Guobao Tian Hong Xu Guoqing Wang 

作者机构：The First Hospital of Jilin UniversityChangchun 130021China Department of PathogenobiologyThe Key Laboratory of ZoonosisChinese Ministry of EducationCollege of Basic Medical ScienceJilin UniversityChangchun 130021China Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Sun Yat-sen University Zhongshan School of MedicineGuangzhou 510275China 

出 版 物：《Biosafety and Health》 (生物安全与健康（英文）)

年 卷 期：2020年第2卷第3期

页      面：164-168页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：supported by grants from the Epidemiology,Early Warning,and Response Techniques of Major Infectious Diseases in the Belt and Road Initiative(#2018ZX10101002) National Natural Science Foundation of China(#81871699) Foundation of Jilin Province Science and Technology Department(#172408GH010234983) 

主　　题：SARS-CoV-2 COVID-19 Death cases Epidemiology Clinical characteristics Risk factors 

摘      要：This study described the epidemiologic and clinical characteristics of patients who died from severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,and pointed out the potential risk factors associated with fatal *** data from 42 death cases due to SARS-CoV-2 infection at Tongji Hospital Affiliated to Huazhong University of Science and Technology,Wuhan,China was ***,clinical detection,laboratory findings,and treatments of the deceased were collected and *** average time between onset of symptoms and admission to the hospitals was 11±5 days of *** the deceased,60%were with *** of them were having fever and bilateral pneumonia on computed tomography,abnormal infection-related biomarkers,and renal *** blood coagulation parameters that appeared in more than half of them,were consistent with disseminated intravascular *** of the patients were treated in the *** on the fact that SARS-CoV-2 infection carries a risk of mortality,we may infer a few older male patients with underlying comorbidities are likely to have the increased *** consciousness level,markers of renal impairment and coagulation abnormalities may be poor prognostic factors.