Fiber-shaped organic electrochemical transistors for biochemical detections with high sensitivity and stability

作     者：Xiaoying Wu Jianyou Feng Jue Deng Zhichang Cui Liyuan Wang Songlin Xie Chuanrui Chen Chengqiang Tang Zhengqi Han Hongbo Yu Xuemei Sun Huisheng Peng Xiaoying Wu;Jianyou Feng;Jue Deng;Zhichang Cui;Liyuan Wang;Songlin Xie;Chuanrui Chen;Chengqiang Tang;Zhengqi Han;Hongbo Yu;Xuemei Sun;Huisheng Peng

作者机构：State Key Laboratory of Molecular Engineering of PolymersDepartment of Macromolecular Scienceand Laboratory of Advanced MaterialsFudan UniversityShanghai 200438China Vision Research LaboratorySchool of Life SciencesState Key Laboratory of Medical NeurobiologyCollaborative Innovation Centre for Brain ScienceFudan UniversityShanghai 200438China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2020年第63卷第9期

页      面：1281-1288页

核心收录：

学科分类：080202[工学-机械电子工程] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 0802[工学-机械工程] 10[医学] 

基　　金：the National Natural Science Foundation of China(21634003 51673043) Ministry of Science and Technology of China(2016YFA0203302) Science and Technology Commission of Shanghai Municipality(17QA1400400) Shanghai Municipal Education Commission(2017-01-07-00-07-E00062) Yanchang Petroleum Group 

主　　题：carbon nanotube fiber flexible organic electrochemical transistor 

摘      要：Precise and continuous monitoring of biochemicals by biosensors assists to understand physiological functions for various diagnostics and therapeutic *** implanted biosensors,small size and flexibility are essential for minimizing tissue damage and achieving accurate ***,the active surface area of sensor decreases as the sensor becomes smaller,which will increase the impedance and decrease the signal to noise ratio,resulting in a poor detection *** advantages of local amplification effect,organic electrochemical transistors(OECTs)constitute promising candidates for high-sensitive ***,their detections in deep tissues are rarely ***,we report a family of implantable,fiber-shaped all-in-one OECTs based on carbon nanotube fibers for versatile biochemical detection including H2O2,glucose,dopamine and *** fiber-shaped OECTs demonstrated high sensitivity,dynamical stability in physiological environment and antiinterference *** implantation in mouse brain,7-day dopamine monitoring in vivo was realized for the first *** fiber-shaped OECTs could be great additions to thelife sciencetool box and represent promising avenue for biomedical monitoring.