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Acute lymphoblastic leukemia in a β-thalassemia intermedia child: A case report

作     者:Laila M Sherief Esmael Goneim Naglaa M Kamal Amr Ibraheim Fuad Alsofiani Abdulraouf Alawur 

作者机构:Department of Pediatric Hematology and OncologyFaculty of MedicineZagazig UniversityZagazig 44511Egypt Department of PediatricsFaculty of MedicineZagazig UniversityZagazig 44511Egypt Department of Pediatric OncologyTanta Cancer InstituteTanta 00202Egypt Department of Pediatrics and Pediatric HepatologyFaculty of MedicineCairo UniversityCairo 21121Egypt Fuad A alsofianiAbdulraouf H AlawurDepartment of PediatricsAlhada Armed Forces HospitalTaif 00966Saudi Arabia 

出 版 物:《World Journal of Clinical Pediatrics》 (世界临床儿科杂志)

年 卷 期:2020年第9卷第1期

页      面:1-6页

学科分类:1002[医学-临床医学] 100202[医学-儿科学] 100214[医学-肿瘤学] 10[医学] 

主  题:Acute lymphoblastic leukemia Thalassemia intermedia Children Malignancies Iron overload Hydroxyurea Case report 

摘      要:BACKGROUNDβ-thalassemia intermedia(βTI)is one of the *** constitutes 10%ofβ-thalassemia cases yet being associated with a better quality of life thanβ-thalassemia major(βTM).CASE SUMMARY We recently reported the first case of acute lymphoblastic leukemia(ALL)from Egypt in a child withβTM,and we herein report the first case of ALL from Egypt in a child withβ*** this report,literature was reviewed for cases of malignancies associated withβTI and the possible factors underling the relationship between the two *** We stress that physicians should have a high index of suspicion of malignancies in thalassemia patients if they present with any suggestive symptoms or signs.

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