Umbilical cord blood application analysis of Guangdong Cord Blood Bank

作     者：Cong-Ying Shi Wei Wei Li-Juan Lyu Qi Wang Shi Cong-Ying;Wei Wei;Lyu Li-Juan;Wang Qi

作者机构：Institution of Guangdong Cord Blood BankGuangdong Women and Children HospitalGuangzhouGuangdong 510663China Department of Experimental CenterGuangzhou Municipality Tianhe Nuoya Bio-engineering Co.LtdGuangzhouGuangdong 510663China Department of Medical Genetic CenterGuangdong Women and Children HospitalGuangzhouGuangdong 511400China Department of Breast Disease CenterGuangdong Women and Children HospitalGuangzhouGuangdong 511400China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2020年第133卷第16期

页      面：1997-1998页

核心收录：

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100215[医学-康复医学与理疗学] 10[医学] 

基　　金：This work was supported by the Guangzhou Municipality Tianhe Nuoya Bioengineering Co.Ltd 

主　　题：Blood diseases hematopoietic 

摘      要：To the Editor:With the development of clinical research and the application of cord blood,the clinical value of umbilical cord blood(UCB)has drawn more and more *** has been increasingly applied to treatments of hematological diseases,autoimmune diseases,and malignant tumors in children and adults[1]and has achieved high overall survival.[1–3]UCB contains substantial amounts of various stem cells,including hematopoietic stem cells(HSC),mesenchymal stem cells,endothelial progenitor cells,and so on[4];among them,HSC are most widely used in study and clinical ***,where UCB HSC are implanted into patients,requires ruining the immune system and hematopoietic system before the *** therapeutic method is UCB infusion,where UCB is regarded as a nutrient,to improve the outcome of peripheral blood HSC transplantation[5]or symptoms via paracrine pathway of UCB stem cells.[6]In addition to the application of allogeneic UCB,autologous UCB has also been used in clinical treatment *** UCB is not limited to treating hemopathy,but also used to treat non-genetic metabolic disease,immune disease,and nervous system injury.[6]