Surface modification of small intestine submucosa in tissue engineering
作者机构：Department of Tissue EngineeringSchool of Fundamental SciencesChina Medical University77 Puhe AvenueShenbei New DistrictShenyang 110122China Department of Cell BiologySchool of Life SciencesChina Medical University77 Puhe AvenueShenbei New DistrictShenyang 110122China and 3Cardiac SurgeryLiaoning First Hospital of China Medical UniversityNo.155 Nanjing StreetHeping DistrictShenyangLiaoning 110122China
出 版 物：《Regenerative Biomaterials》 (再生生物材料（英文版）)
年 卷 期：2020年第7卷第4期
页 面：339-348页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程]
基 金：supported by the National Natural Science Foundation of China(No.81571919) LiaoNing Revitalization Talents Program(No.XLYC1907124)
主 题：small intestinal submucosa surface modification in vitro scaffold tissue engineering
摘 要：With the development of tissue engineering,the required biomaterials need to have the ability to promote cell adhesion and proliferation in vitro and in ***,surface modification of the scaffold material has a great influence on biocompatibility and functionality of *** small intestine submucosa(SIS)is an extracellular matrix isolated from the submucosal layer of porcine jejunum,which has good tissue mechanical properties and regenerative activity,and is suitable for cell adhesion,proliferation and *** recent years,SIS is widely used in different areas of tissue reconstruction,such as blood vessels,bone,cartilage,bladder and ureter,*** paper discusses the main methods for surface modification of SIS to improve and optimize the performance of SIS bioscaffolds,including functional group bonding,protein adsorption,mineral coating,topography and formatting modification and drug *** addition,the reasonable combination of these methods also offers great improvement on SIS surface *** article makes a shallow review of the surface modification of SIS and its application in tissue engineering.
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