Debate on Bacille Calmette-Guérin vaccination against COVID-19: Is it worth performing clinical trials?
Debate on Bacille Calmette-Guérin vaccination against COVID-19: Is it worth performing clinical trials?作者机构:University of OsloFaculty of MedicineOsloNorway Norwegian Institute of Public Health(NIPH)Division of Infection Control and Environmental HealthOsloNorway Graduate School of Biomedical and Health SciencesHiroshima UniversityJapan
出 版 物:《Biosafety and Health》 (生物安全与健康(英文))
年 卷 期:2020年第2卷第3期
页 面:113-114页
学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
主 题:Bacille Calmette-Guérin COVID-19 Non-specific effect RCT Clinical trial
摘 要:The non-specific beneficial effects of Bacille Calmette-Guérin(BCG)vaccination suggest that this vaccine might play a role in protecting individuals against severe coronavirus disease 2019(COVID-19).Several studies propose that BCG vaccination may increase the body s immunity,thereby preventing respiratory infections caused by other respiratory *** the number of deaths due to COVID-19 is increasing rapidly and there is no specific treatment available to date,scientists are evaluating the effectiveness of already approved drugs as therapies against COVID-19,and the results were found to vary widely:from no significant effect being observed to a reduction in the time taken for clinical *** study thus aims to evaluate whether it is worth performing clinical trials to examine the effects of the BCG vaccine on *** herein emphasize the need to conduct phase III randomized controlled trials with adequate sample size and quality to investigate the effects of the BCG vaccine on *** the event that BCG vaccination provides non-specific protection against COVID-19,administering it could be helpful in controlling the transmission of COVID-19 and other infectious diseases during future pandemics.