Cellular and humoral immune interactions between Drosophila and its parasitoids
作者机构：State Key Laboratory of Rice Biology&Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and InsectsInstitute of Insect SciencesZhejiang University.HangzhouChina USD A Agricultural Research ServiceBiological Control of Insects Research LaboratoryColumbiaMissouriUnited States
出 版 物：《Insect Science》 (昆虫科学（英文版）)
年 卷 期：2021年第28卷第5期
页 面：1208-1227页
核心收录：
学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 09[农学] 0904[农学-植物保护] 0901[农学-作物学] 0713[理学-生态学]
基 金：the Key Program of Na-tional Natural Science Foundation of China(31830074) the Major International(Regional)Joint Research Project of NSFC(31620103915) the Program for Chinese Inno-vation Team in Key Areas of Science and Technology of the Ministry of Science and Technology of the People's Republic of China(2016RA4008) the Program for Chinese Outstanding Talents in Agricultural Scientific Research of the Ministry of Agriculture and Rural Af-fairs of the People's Republic of China
主 题：Drosophilas immunity parasitoid venom virus-like particles
摘 要：The immune interactions occurring between parasitoids and their host insects,especially in Drosophila-wasp models,have long been the research focus of insect immunology and *** infestation in Drosophila is counteracted by its multiple natural immune defense systems,which include cellular and humoral immunity,Occurring in the hemocoel,cellular immune responses involve the proliferation,differentiation,migration and spreading of host hemocytes and parasitoid encapsulation by ***,humoral immune responses rely more heavily on melanization and on the Toll,Imd and Jak/Stat immune pathways associated w ith antimicrobial peptides along with stress *** the wasps side,successful development is achieved by introducing various virulence factors to counteract immune responses of *** or all of these factors manipulate the host s immunity for successful *** we review current knowledge of the cellular and humoral immune interactions between Drosophila and its parasitoids,focusing on the defense mechanisms used by Drosophila and the strategies evolved by parasitic wasps to outwit it.
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