Vascularization is the next challenge for skin tissue engineering as a solution for burn management
作者机构：Department of Hand Surgery and Plastic Surgery and BurnsLinkoing University Hospital58185LinkoingOtergolandSweden The Department of Biomedical and Clinical SciencesLinkoing UniversityLinkoing University Hospital58183LinkoingOtergolandSweden Faculty of BiotechnologyMSA University26 July Mehwar Road125856th October City.Egypt
出 版 物：《Burns & Trauma》 (烧伤与创伤（英文）)
年 卷 期：2020年第8卷第1期
页 面：174-185页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Burn Skin Regeneration Tissue engineering Vascularization
摘 要：Skin regeneration represents a promising line of management for patients with skin loss,including burn *** current approach of spraying single cells over the defective areas results in variable success rates in different *** modern approach is to synthesize a multilayer skin construct that is based on autologous stem *** of the main complications with different types of transplants is sloughing due to the absence of proper *** proper vascularization will be crucial for the integration of skin constructs with the surrounding *** of the right cells with scaffolds of proper physico-chemical properties,vascularization can be markedly *** material effect,pore size and adsorption of certain proteins,as well as the application of appropriate growth factors,such as vascular endothelial growth factors,can have an additive effect.A selection of the most effective protocols is discussed in this review.
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