咨询与建议

看过本文的还看了

相关文献

该作者的其他文献

文献详情 >Efficacy and brain mechanism o... 收藏

Efficacy and brain mechanism of transcutaneous auricular vagus nerve stimulation for adolescents with mild to moderate depression:Study protocol for a randomized controlled trial

Efficacy and brain mechanism of transcutaneous auricular vagus nerve stimulation for adolescents with mild to moderate depression: Study protocol for a randomized controlled trial

作     者:Xue Xiao Xiaobing Hou Zhangjing Zhang Ying Li Xue Yu Yanhui Wang Jing Tian Ke Xu Xiao Xue;Hou Xiaobing;Zhang Zhangjing;Li Ying;Yu Xue;Wang Yanhui;Tian Jing;Xu Ke

作者机构:Department of PsychiatryBeijing First Hospital of Integrated Chinese and Western MedicineBeijingChina Department of Acupuncture and MoxibustionBeijing First Hospital of Integrated Chinese and Western MedicineBeijingChina Department of Chinese MedicineUniversity of Hong Kong Shenzhen Hospital(HKU‐SZH)ShenzhenGuangdongChina Department of PsychiatryBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Department of CardiologyBeijing First Hospital of Integrated Chinese and Western MedicineBeijingChina Department of Medical imagingGuang’anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina 

出 版 物:《Pediatric Investigation》 (儿科学研究(英文))

年 卷 期:2020年第4卷第2期

页      面:109-117页

学科分类:1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

主  题:Depression Adolescent Transcutaneous auricular vagus nerve stimulation(taVNS) 

摘      要:Background Depression is a common mental illness in childhood and adolescence,with an incidence of 4%–5%;it can lead to impairments in learning and social *** auricular vagus nerve stimulation(taVNS)is a commonly used method of auricular acupuncture point stimulation,which is regarded as an effective treatment for adults with *** aim of this study was to investigate the efficacy and mechanism of taVNS for adolescents with mild to moderate *** This randomized controlled clinical trial will include 120 patients aged 12–16 years,all of whom are diagnosed with mild to moderate *** will be randomly assigned to a taVNS group and a drug control group(sertraline hydrochloride)at a ratio of 1:*** will be evaluated using the 17‐item Hamilton Depression Scale,Hamilton Anxiety Rating Scale,Self‐Rating Depression Scale,Self‐Rating Anxiety Scale,and Pittsburgh Sleep Quality Index scores at baseline,as well as at the 2nd,4th,6th,8th,and 12th *** investigate the underlying neural mechanisms of taVNS treatment from the perspective of the default mode network,multimodal magnetic resonance imaging(MRI;i.e.,structural MRI[sMRI],resting state MRI[rsMRI],and pseudocontinuous arterial spin‐labeled[pcASL]MRI)will be used to compare cerebral images among *** data will also be collected from 40 healthy volunteers to assess whether the participants exhibit normal development of structural and functional *** Depression is the most common mental disorder in *** treatment can improve depression symptoms;however,the side effects of drug treatments are often *** study proposes a simple physiotherapy that aims to treat adolescents with mild to moderate *** mechanism of taVNS in the treatment of depression will also be *** results of this study will provide evidence to guide the application of taVNS in adolescents with depression.

读者评论 与其他读者分享你的观点

用户名:未登录
我的评分