Thick tongue coating: diagnostic markers for metastatic colorectal cancer?

作     者：Hao-Ran Zhang Xue Yang Cui-Hong Zhu Dan Chen Xiong-Zhi Wu 

作者机构：Tianjin Hospital of Integrated Traditional Chinese and Western MedicineTianjin 300100China Department of Medical OncologyTianjin Medical University General HospitalTianjin 300052China Tianjin Cancer Hospital Airport HospitalTianjin 300308China Tianjin Jingui Linglan Science and Technology Ltd.Tianjin 300000China Tianjin Medical UniversityTianjin 300384China 

出 版 物：《TMR Cancer》 (TMR肿瘤)

年 卷 期：2020年第3卷第4期

页      面：144-152页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Colorectal cancer Tongue coating thickness Prognosis EGF lactic dehydrogenase Diagnostic markers 

摘      要：Background:According to World Health Organization,colorectal cancer is the third most common cancer in the *** prognosis assessment and condition judgment of the colorectal cancer remains a challenge ***,identification of diagnostic markers to evaluate the prognosis of colorectal cancer clinically should be urgently *** have observed that a lot of cancer patients had thick tongue clinically,but what is the relationship between tongue coating and the tumor?Methods:Seventy-four patients with colorectal carcinoma were collected through the outpatients of Tianjin Medical University Cancer Institute and Hospital from May 2010 to September 2011,in which there were 49 patients confirmed with recurrence or *** photos of patients’tongue were taken with a SONY camera in the same room and under constant conditions such as brightness or *** equation predicting thickness of tongue coating was constructed using binary logistic regression *** optimal cut off of probabilities to diagnosis thick tongue coating was determined by receiver operating curve analysis.χ2 test for paired data and kappa test were used to determine the diagnostic value for recurrence and/or metastasis in colorectal cancer ***-Smirnov test was used to determine the distribution of ALT,AST,ALP ALB,TP,GLO,TBIL,DBIL,GGT,LDH,GLU,UA,CA724,CA199,CA242 and *** with the skewed distribution were presented as median(quartile interval).The association between the thickness of tongue coating and clinical-pathological character was evaluated by chi square test and two-independent-sample *** two-independent-samplesχ2 was used to determine whether there were significant differences in the thin coating and thick coating between patients with recurrence and/or metastasis and patients without recurrence and/or ***-Meier method was used to analyze survival *** analysis was performed by SPSS(version 16.0).Resul